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AVANÇOS RECENTES NO USO DE VETORES VIRAIS NA TERAPIA GÊNICA CONTRA INFECÇÕES POR HPV: UMA REVISÃO DE LITERATURA

Doi: 10.47094/XXXSBM.2025/33

PALAVRAS CHAVE: Adenovírus oncolíticos. Resposta imune. Vacinas.

KEYWORDS: Oncolytic adenoviruses. Immune response. Vaccines.

ABSTRACT:
Introduction: Human papillomavirus (HPV) is a virus that affects epithelial cells and poses a significant public health challenge. It is classified into high-risk groups, which are associated with a higher risk of developing cancer, and low-risk groups, which are more frequently associated with the development of benign lesions. In this context, gene therapy emerges as a promising alternative for HPV treatment, with viral vectors playing a crucial role in this new strategy. Gene therapy uses recombinant DNA techniques to replace or manipulate defective genes. Viral vectors transport the therapeutic material to target cells. Objective: To conduct a literature review on advances between 2019 and 2025 in the use of viral vectors in gene therapy for HPV.

Autores

  • Izabela Laís Alves dos Santos

  • Arthur Aurélio Pessoa da Cruz

  • Esmeralda Bezerra de Lima

  • Giovanna Ângela da Silva Plinio

  • José Rivelino Maurício Freire Santos

  • Júlio Batista do Nascimento

  • Maira Freitas Matos Costa

  • Marina Linhares Lara

  • Vitória Jamylly Nunes Monteiro

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