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COVID-19 LONGA: ASPECTOS CLÍNICOS E FATORES DE RISCO EM CRIANÇAS E ADOLESCENTES

Doi: 10.47094/ICOLUBRAIS.2021/22

PALAVRAS CHAVE: Infecção viral. Sequelas. Suscetibilidade.

KEYWORDS: Viral infection. Sequelae. Susceptibility.

ABSTRACT:
Introduction: Long-term COVID-19 is defined as the persistence of typical symptoms of COVID-19 for more than 4 weeks after the onset of the acute phase. This condition in adults is increasingly documented, but the involvement in children and adolescents still needs to be better elucidated. Objectives: To review publications focused on the investigation of long-term COVID-19 in children and adolescents, identifying the main symptoms described and risk factors related to clinical worsening in this age group. Methods: It consisted of a literature review of studies published in the year 2021, present in the PubMed database. Articles in English were included that investigated long-term COVID-19 in children and adolescents (& #60; 18 years) laboratory-confirmed for COVID-19 during the acute phase. Bibliographic reviews were not included. Results: A study by Asadi Pooya et al (2021), in Iran, showed that 26 children and adolescents had symptomatic sequelae related to COVID-19 long after 3 months of acute involvement. The most frequent symptoms were fatigue, body weakness, low exercise tolerance and shortness of breath. Similarly, the investigation by Buonsenso et. al. (2021) demonstrated that fatigue, insomnia, headache and muscle pain and nasal congestion were frequent in 129 children and adolescents evaluated 1 month after the acute phase in Italy. Osmanov et. al. (2021), in a longitudinal study where 518 children and adolescents were followed for more than 5 months in Russia, showed that fatigue was the most frequent persistent symptom, followed by sensory and sleep complications. The same authors described that: older age; admission to the Intensive Care Unit (ICU), pre-existing allergic diseases and muscle pain at the time of admission to the hospital, favored the risk of developing persistent symptoms of COVID-19. Final considerations: These data suggest that children under 18 are susceptible to developing persistent symptoms of COVID-19 for several months after the onset of acute symptoms and, therefore, understanding this involvement is important for the health of children and adolescents, impacting public health decision-making involving these age groups.

Autores

  • Alyne Talita Martires Cabral

  • Ana Cristina Carneiro Martins

  • Brena Suelen Gama Macias

  • Carmem Aliandra Freire De Sá

  • Daniel Carvalho De Menezes

  • Elizabeth Ferreira De Miranda

  • Ingrid Do Socorro Da Silva Pires De Almeida

  • Joice Cristina Gomes De Sousa

  • Sara De Souza Pereira

  • Silvia Mara Gomes Passos Miranda

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