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CÉLULAS-TRONCO MESENQUIMAIS NA ORTOPEDIA REGENERATIVA: AVANÇOS, APLICAÇÕES E PERSPECTIVAS TERAPÊUTICAS

Doi: 10.47094/978-65-284-0234-2/20

PALAVRAS CHAVE: Células-Tronco Mesenquimais. Ortopedia. Regeneração Celular.

KEYWORDS: Mesenchymal Stem Cells. Orthopedics. Cell Regeneration.

ABSTRACT:
INTRODUCTION: Osteoarticular injuries challenge orthopedics due to the limited regeneration of cartilage and bone. In this scenario, mesenchymal stem cells (MSCs) stand out, with multipotent, immunomodulatory, and regenerative action. Derived from bone marrow, adipose tissue, or umbilical cord, they differentiate into chondrocytes and osteoblasts, favoring tissue repair. Intra-articular or intraosseous applications promote pain relief, functional improvement, and regeneration in osteoarthritis and fractures. This work reviews their main clinical applications. OBJECTIVES: To investigate the therapeutic potential of mesenchymal stem cells in regenerative orthopedics with clinical evidence and current perspectives.

Autores

  • Daniel Cena Ramos

  • Eduardo Ferreira Naves

  • Ernandes Silva-Filho

  • Gabrielly Pereira Alves

  • Rafael Henrique Novotny

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