A RELAÇÃO ENTRE INFLAMAÇÃO CRÔNICA DE BAIXO GRAU (INFLAMMAGING) E O DESENVOLVIMENTO DE SÍNDROMES GERIÁTRICAS

Doi: 10.47094/IICOLUBRASMU.2025/RE.10

PALAVRAS CHAVE: Envelhecimento. Fragilidade. Declínio funcional.

KEYWORDS: Aging. Frailty. Functional decline.

ABSTRACT:
INTRODUCTION
Inflammaging does not correspond to acute inflammation, but rather to a continuous and silent immune activation caused by mitochondrial dysfunction, accumulation of senescent cells, changes in the intestinal microbiota, and prolonged antigenic stimuli. According to Giunta et al. (2022), it is a homeostatic imbalance that precedes and contributes to a chronic inflammatory state, directly affecting the health of older adults.

Autores

• Aline Pertile Remor

• Claudina Mendes Horevicht

• João Vitor Lewe Colibaba

• Luana Patricia Marmitt

• Sirlei Favero Cetolin