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DEFICIÊNCIA DE VITAMINA D E SEUS IMPACTOS NA SAÚDE ÓSSEA DE PACIENTES COM DIABETES TIPO 1: REVISÃO SISTEMÁTICA

Doi: 10.47094/CESMED.2025/4

PALAVRAS CHAVE: Diabetes tipo 1. Saúde óssea. Vitamina D.

KEYWORDS: Type 1 Diabetes. Bone Health. Vitamin D.

ABSTRACT:
INTRODUCTION: Vitamin D is crucial for bone health, regulating calcium and phosphorus. In type 1 diabetes (T1D), its deficiency is associated with bone problems and glycemic control, increasing the risk of osteoporosis and fractures. T1D, an autoimmune disease, causes insulin deficiency and chronic hyperglycemia, reducing bone mineral density (BMD) and increasing the risk of fractures. The relationship between T1D and vitamin D deficiency is bidirectional: a lack of vitamin D can predispose to T1D, affecting autoimmunity and insulin sensitivity, while T1D can lead to vitamin D deficiency, especially in cases of diabetic nephropathy. This study analyzes the effects of vitamin D deficiency on bone health in patients with T1D, highlighting the importance of early interventions. OBJECTIVES: This work aims to gather and analyze the available scientific evidence on the impacts of vitamin D deficiency on the bone health of patients with type 1 diabetes mellitus.

Autores

  • Ana Letícia Teixeira Couto

  • Bruna Gonçalves Albernaz

  • Flavio José Teles de Morais

  • Jordana Quiel Barros Martins

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