Publicar

MECANISMOS IMUNOLÓGICOS DA LEISHMANIOSE: RESPOSTA DO HOSPEDEIRO E EVASÃO PARASITÁRIA

Doi: 10.47094/CESMED.2025/44

PALAVRAS CHAVE: Interações Hospedeiro-Parasita. Imunologia. Leishmaniose.

KEYWORDS: Host-Parasite Interactions. Immunology. Leishmaniasis.

ABSTRACT:
INTRODUCTION: Leishmaniasis is a tropical disease endemic in Brazil caused by protozoa of the genus Leishmania sp. and transmitted by the bite of infected sandflies. The immune response varies depending on the host-parasite interaction, influencing the systemic spread of the infection. Understanding the immunological modulation of the host response and the parasite' s evasion strategies aids in disease control, as progressive immunosuppression leads to potential bacterial infections, organ dysfunction, and death. OBJECTIVE: To investigate the immunological mechanisms that determine the host response to Leishmania sp. infection.

Autores

  • Lara Auad Forte

  • Larissa Pereira Santos

  • Letícia Moraes Brito Barros

  • Marcus Vinicius Milki

Download