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HIPERTERMIA MALIGNA: ASPECTOS CLÍNICOS, GENÉTICOS E TERAPÊUTICOS

Doi: 10.47094/978-65-284-0273-1/11

PALAVRAS CHAVE: Hipertermia maligna. Fatores de risco. Tratamento.

KEYWORDS: Malignant hyperthermia. Risk factors. Treatment.

ABSTRACT:
Introduction: Malignant hyperthermia (MH) is a rare and serious condition characterized by a hypermetabolic response to anesthetic agents, resulting in muscle rigidity, tachycardia, hyperthermia, and metabolic alterations. It occurs during general anesthesia, especially in genetically predisposed patients. Although infrequent, when not diagnosed and treated quickly, it presents a high mortality rate. The treatment of choice is the drug dantrolene sodium, associated with the immediate discontinuation of triggers and supportive measures. Given its severity and unpredictability, rapid intervention is essential to reduce complications. Objectives: To recognize risk factors and causes of MH, as well as to analyze complications resulting from the absence of adequate treatment.

Autores

  • Andressa Cardoso Faria

  • Camily Parreira Tonaco

  • Ernandes da Silva Filho

  • Gabriela Costa de Castro

  • Maria Claudia Costa Américo de Melo

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